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immunological infertility

Immunological Infertility
IHR provides effective treatment programs for immunological infertility.

Among infertility experts, there is uncertainty and even controversy as to whether immunological condtions and abnormal female immune functions exert a causitive effect upon infertility. There are doctors who believe there is no connection, and those who believe there is. For the record, IHR believes immunological infertility is quite real, for which we pursue various treatment options and a few experimental protocols. Our strategy is to learn as much as we can about the infertility in question before reaching any definitive diagnosis, and to help to that end we offer the best diagnostic test and treatment options available. The IHR experts work closely with couples undergoing the many different types of assisted fertility treatments available. We are renowned for our specialized knowledge and high infertility success rates even in difficult cases. IHR's expertise in immunological infertility lies in our willingness and ability to individualize our approach to best suit each and every one of our patients. If you have any questions as you review the material on female infertility, please contact us for a FREE Immunological Infertility E-Mail Consultation.

Immune infertility reproductive disorder affects both men and women, causing their immune systems to wage war on sperm. Women with immune infertility produce antisperm antibodies, ASA, in their reproductive tracts. These antibodies neutralize sperm by clumping them together and poking holes in their membranes. ASA also coats over receptors involved in sperm-egg binding and fertilization.

An estimated 12 to 15 percent of unexplained infertility in women is linked to ASA. In rare cases, these antisperm antibodies have caused women to go into anaphylactic shock upon insemination.

In men, immune infertility has several causes, including vasectomies. After a vasectomy, the body can no longer release sperm and produces antibodies to help engulf and clear them. ASA persists for years in the circulation of vasectomized men and may cause reduced fertility in those who have the procedure reversed (vasovasostomy).

There is no clearly defined treatment for immunological infertility. Historically, the best results seem to follow a trial of ovulation induction and insemination followed by in vitro fertilization with sperm washing and intra-cytoplasmic sperm injection, ICSI (a process that involves injecting a sperm directly into an egg).

IHR has treatments for a variety of conditions, including immunological infertility and many others. Perhaps less known is our work with individuals and couples who are considering assisted reproduction, but who are uncertain of their next step. We encourage anyone, before they make a decision, to consult with us. Currently, we are offering a FREE Immunological Infertility E-Mail Consultation.