In Vitro Maturation (IVM)
IVM is a revolutionary fertility treatment developed to provide a safer and a cheaper alternative to conventional IVF.
In Vitro Maturation (IVM) is a relatively new procedure similar to in vitro fertilization (IVF), yet with a notable difference. IVF utilizes a regimen of medications to bring a patient's eggs to maturity before they are removed from the ovary; IVM retrieves eggs while they are still in the immature stage, and brings them to maturity in the laboratory (in vitro).
IHR's expertise in In Vitro Maturation (IVM) lies in our willingness and ability to individualize our approach to best suit each and every one of our patients. If you have any questions as you review the material on In Vitro Maturation (IVM) , please contact us for a FREE In Vitro Maturation (IVM) E-Mail Consultation..
Immature eggs are collected from unstimulated or minimally stimulated ovaries under ultrasound scan guidance. The immature eggs are then matured in the laboratory for 24-48 hours using culture medium with added small quantities of hormones. Intracytoplasmic sperm injection (ICSI) is used for fertilization of the matured eggs. The resulting embryos are transferred to the women's wombs.
Stimulated IVF is associated with the risk of developing ovarian hyperstimulation syndrome (OHSS) which is a potentially fatal condition and IVM eliminates this risk because it does not involve ovarian stimulation. Also, IVM is less expensive than IVF because it does not involve taking costly gonadotropin injections and involve less monitoring. Moreover, IVM is a shorter treatment regimen compared with in vitro fertilization.
IVM is ideal for patients who are unable to tolerate the effects of the medications necessary to urge oocytes to maturity, such as fertility preservation for cancer patients who are early in recovery and on other medications, for these patients, the same treatments that are used to trigger oocytes to transition to maturity, may also cause a stimulative effect on deadly cancer cells. Other examples include as an alternative to IVF for women with PCOS; these patients are at significant risk of OHSS, as an alternative to IVF for younger women with normal menstrual cycles, IVM being less costly and safer, for salvaging immature eggs collected during a standard IVF/ICSI (when unexpectedly a significant number of eggs collected are immature), for women who will benefit most from in vitro maturation are women aged 35 and younger and have antral follicle count of 10 or more.
As well, other kinds of patients may benefit from IVM, incuding some Prematurely Aging Ovary patients. IVM is also a way to avoid expensive gonadotropins and risks related to ovarian hyperstimulation.
Perhaps less known is our work with individuals and couples who are considering assisted reproduction, but who are uncertain of their next step. We encourage anyone, before they make a decision, to consult with us. Currently, we are offering a FREE In Vitro Maturation (IVM) E-Mail Consultation.