Preimplantation Genetic Diagnosis (PGD)
Parents wish for their children to be healthy. They cannot change their own genetics but parents do have the option, and most feel they have the obligation, to provide their future children a chance for the best life possible and to spare them inherited debilitating genetic disease. IHR has the experience and the expertise to assist these couples to make the best reproductive choice suitable for them to conceive a healthy baby, and the understanding of the emotional roller-coaster, which they are going through.
Preimplantation genetic testing is a technique used to identify genetic defects in embryos created through in vitro fertilization (IVF) before pregnancy. Preimplantation genetic diagnosis (PGD) refers specifically to when one or both genetic parents have a known genetic abnormality and testing is performed on an embryo to determine if it also carries a genetic abnormality. In contrast, preimplantation genetic screening (PGS) refers to techniques where embryos from presumed chromosomally normal genetic parents are screened for aneuploidy. Because only unaffected embryos are transferred to the uterus for implantation, preimplantation genetic testing provides an alternative to current post-conception diagnostic procedures (ie, amniocentesis or chorionic villus sampling), which are frequently followed by the difficult decision of pregnancy termination if results are unfavorable. PGD and PGS are presently the only options available for avoiding a high risk of having a child affected with a genetic disease prior to implantation. It is an attractive means of preventing heritable genetic disease, thereby eliminating the dilemma of pregnancy termination following unfavorable prenatal diagnosis.
Through PGD techniques, we are able to test for many different genetic diseases. Some of our families request PGD for a specific genetic condition running in their family, such as cystic fibrosis, Tay Sachs disease, muscular dystrophy or Fragile X syndrome. Other couples request genetic testing for chromosome problems, such as Down syndrome, trisomy 18, trisomy 13 and Marfan syndrome, and in order to improve their chances of getting pregnant during in vitro fertilization. By choosing to pursue PGD, you will significantly reduce the chances for your baby to be affected with a specific genetic condition.
In addition, in the course of the PGD/PGS procedure, doctors receive information on the predicting gender, which is useful to prevent X-linked disorders and for family balancing.
IHR offer advanced treatments for a variety of conditions, including female and male infertility, unexplained infertility, diminished ovarian reserve, ovulatory dysfunctions, endometriosis, immunological infertility, egg donation, surrogacy, and many others. Perhaps less known is our work with individuals and couples who are considering assisted reproduction, but who are uncertain of their next step. We encourage anyone, before they make a decision, to consult with us. Currently, we are offering a FREE Preimplantation Genetic Diagnosis E-Mail Consultation.